Cellular/Molecular CLIP-170 and IQGAP1 Cooperatively Regulate Dendrite Morphology
نویسندگان
چکیده
Lukasz Swiech,1 Magdalena Blazejczyk,1,2 Malgorzata Urbanska,1 Patrycja Pietruszka,1 Bjorn R. Dortland,3 Anna R. Malik,1 Phebe S. Wulf,3,4 Casper C. Hoogenraad,3,4 and Jacek Jaworski1 1Laboratory of Molecular and Cellular Neurobiology, International Institute of Molecular and Cell Biology, 02-109 Warsaw, Poland, 2Nencki Institute of Experimental Biology, 02-093 Warsaw, Poland, 3Department of Neuroscience, Erasmus Medical Center, 3000CA Rotterdam, The Netherlands, and 4Department of Cell Biology, Faculty of Science, Utrecht University, 3584CH Utrecht, The Netherlands
منابع مشابه
CLIP-170 and IQGAP1 cooperatively regulate dendrite morphology.
Dendritic arbors are compartments of neurons dedicated to receiving synaptic inputs. Their shape is an outcome of both the intrinsic genetic program and environmental signals. The microtubules and actin cytoskeleton are both crucial for proper dendritic morphology, but how they interact is unclear. The present study demonstrates that microtubule plus-end tracking protein CLIP-170 and actin-bind...
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